"Significant reductions in the number of comedones, papules, and pustules were observed in the treatment group compared with placebo after 2 months. Also, ADI was decreased 63.49% in the treatment versus 4.5% in the placebo groups. No adverse event was recorded. N. sativa hydrogel had significant effects on improving the symptoms of acne vulgaris with acceptable tolerability. "
Soleymani, Samaneh et al. “The effect of a hydrogel made by Nigella sativa L. on acne vulgaris: A randomized double-blind clinical trial.” Phytotherapy research : PTR vol. 34,11 (2020): 3052-3062. doi:10.1002/ptr.6739
